References

1. Simopoulos AP. Overview of evolutionary aspects of omega 3 fatty acids in the diet. World Rev Nutr Diet. 1998;83:1-11.

2. Simopoulos AP. Essential fatty acids in health and chronic disease. Am J Clin Nutr. 1999; 70(3 Suppl):560S - 569S.

3. Blasbalg TL, Hibbeln JR, Ramsden CE, Majchrzak SF, Rawlings RR. Changes in consum ption of omega-3 and omega-6 fatty acids in the United States during the 20th century. Am erican Journal of Clinical Nutrition. 2011;93(5):950-962. doi:10.3945/ajcn.110.006643.

4. Singh T, Newman AB. Inflammatory markers in population studies of aging. Ageing Res R ev. 2011;10(3):319-329. doi:10.1016/j.arr.2010.11.002.

5. Dyerberg J, Madsen P, Møller JM, Aardestrup I, Schmidt EB. Bioavailability of marine n-3 f atty acid formulations. Prostaglandins, Leukotrienes and Essential Fatty Acids. 2010;83(3) :137-141. doi:10.1016/j.plefa.2010.06.007.

6. Lawson LD, Hughes BG. Human absorption of fish oil fatty acids as triacylglycerols, free a cids, or ethyl esters. Biochem Biophys Res Commun. 1988;152(1):328-335.

7. Zargar A, Ito MK. Long chain omega-3 dietary supplements: a review of the National Libra ry of Medicine Herbal Supplement Database. Metab Syndr Relat Disord. 2011;9(4):255-27 1. doi:10.1089/met.2011.0004.

8. Opperman M, Marais de W, Spinnler Benade AJ. Analysis of omega-3 fatty acid content of South African fish oil supplements. Cardiovasc J Afr. 2011;22(6):324-329. doi:10.5830/CV JA-2010-080.

9. Product Review: Fish Oil and Omega-3 Fatty Acid Supplements Review (Including Krill, Al gae, Calamari, Green-lipped Mussel Oil). ConsumerLab.com. June 2015. https://www.con sumerlab.com/reviews/fish_oil_supplements_review/omega3/.

10. Flachs P, Horakova O, Brauner P, et al. Polyunsaturated fatty acids of marine origin upreg ulate mitochondrial biogenesis and induce beta-oxidation in white fat. Diabetologia. 2005;4 8(11):2365-2375. doi:10.1007/s00125-005-1944-7.

11. Stonehouse W, Conlon CA, Podd J, et al. DHA supplementation improved both memory a nd reaction time in healthy young adults: a randomized controlled trial. Am J Clin Nutr. 201 3;97(5):1134-1143. doi:10.3945/ajcn.112.053371.

12. Flachs P, Mohamed-Ali V, Horakova O, et al. Polyunsaturated fatty acids of marine origin i nduce adiponectin in mice fed a high-fat diet. Diabetologia. 2006;49(2):394-397. doi:10.10 07/s00125-005-0053-y.

13. Högström M, Nordström P, Nordström A. n-3 Fatty acids are positively associated with pe ak bone mineral density and bone accrual in healthy men: the NO2 Study. Am J Clin Nutr . 2007;85(3):803-807.

14. Allaire J, Couture P, Charest A, et al. DHA is more potent than EPA in attenuating cardiom etabolic risk in men and women: a randomized double-blind, placebo-controlled crossover trial. FASEB J. 2016;30(1 Supplement):130.1-130.1.

15. SourceOne Global Partners: VesiSorb Delivery System. 2012. www.Source-1-Global.com.

16. Rubio-Rodríguez N, de Diego SM, Beltrán S, Jaime I, Sanz MT, Rovira J. Supercritical flui d extraction of fish oil from fish by-products: A comparison with other extraction methods. Journal of Food Engineering. 2012;109(2):238-248. doi:10.1016/j.jfoodeng.2011.10.011.

17. Weldon SM, Mullen AC, Loscher CE, Hurley LA, Roche HM. Docosahexaenoic acid induc es an anti-inflammatory profile in lipopolysaccharide-stimulated human THP-1 macrophag es more effectively than eicosapentaenoic acid. J Nutr Biochem. 2007;18(4):250-258. doi: 10.1016/j.jnutbio.2006.04.003.

18. Ulven SM, Kirkhus B, Lamglait A, et al. Metabolic Effects of Krill Oil are Essentially Similar to Those of Fish Oil but at Lower Dose of EPA and DHA, in Healthy Volunteers. Lipids. 20 11;46(1):37-46. doi:10.1007/s11745-010-3490-4.

19. Ramprasath VR, Eyal I, Zchut S, Jones PJ. Enhanced increase of omega-3 index in health y individuals with response to 4-week n-3 fatty acid supplementation from krill oil versus fis h oil. Lipids in Health and Disease.2013;12(1):178. doi:10.1186/1476-511X-12-178.

20. Crawford MA, Bloom M, Broadhurst CL, et al. Evidence for the unique function of docosah exaenoic acid during the evolution of the modern hominid brain. Lipids. 1999;34 Suppl:S3 9-S47. 21. Aranceta J, Pérez-Rodrigo C. Recommended dietary reference intakes, nutritional goals a nd dietary guidelines for fat and fatty acids: a systematic review. Br J Nutr. 2012;107 Supp l 2:S8-S22. doi:10.1017/S0007114512001444.